Postdoctoral researcher
Dr. ZENG Judeng
BSc (Hons), MPhil, PhD
Scientific Officer
Department of Anaesthesia and Intensive Care
The Chinese University of Hong Kong

Publications
- Zeng, J.#, Xie, C#., Huang, Z., Cho, C. H., Chan, H., Li, Q., Ashktorab, H., Smoot, D. T., Wong, S. H., Yu, J., Gong, W., Liang, C., Xu, H., Chen, H., Liu, X., Wu, J. C. Y., Ip, M., Gin, T., Zhang, L., Chan, M. T. V., Hu, W., & Wu, W. K. K. (2024). LOX-1 acts as an N6-methyladenosine-regulated receptor for Helicobacter pylori by binding to the bacterial catalase. Nat Commun, 15(1), 669. [IF2023=14.7]
- Chen, M., Fang, Y., Liang, M., Zhang, N., Zhang, X., Xu, L., Ren, X., Zhang, Q., Zhou, Y., Peng, S., Yu, J., Zeng, J.*, & Li, X*. (2023). The activation of mTOR signalling modulates DNA methylation by enhancing DNMT1 translation in hepatocellular carcinoma. J Transl Med, 21(1), 276. [IF2023=6.1]
- Chen, H., Zhang, X., Su, H., Zeng, J., Chan, H., Li, Q., Liu, X., Zhang, L., Wu, W.K.K., Chan, M.T.V., and Chen, H. (2023). Immune dysregulation and RNA N6-methyladenosine modification in sepsis. Wiley Interdiscip Rev RNA, e1764. 10.1002/wrna.1764. [IF2023=6.4]
- Zeng, J., Xie, C., Zhang, L., Liu, X., Chan, M.T.V., Wu, W.K.K., and Chen, H. (2022). Host Cell Antimicrobial Responses against Helicobacter pylori Infection: From Biological Aspects to Therapeutic Strategies. Int J Mol Sci 23. 10.3390/ijms231810941. [IF2023=4.9]
- Wang, X., Hu, W., Li, X., Huang, D., Li, Q., Chan, H., Zeng, J., Xie, C., Chen, H., Liu, X., Gin, T., Wang, M.H., Cheng, A.S.L., Kang, W., To, K.F., Plewczynski, D., Zhang, Q., Chen, X., Chan, D.C.W., Ko, H., Wong, S.H., Yu, J., Chan, M.T.V., Zhang, L., and Wu, W.K.K. (2022). Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution. Cancer research 82, 1482-1491. [IF2023=12.5]
- Sun, X., Liu, Y., Huang, Z., Xu, W., Hu, W., Yi, L., Liu, Z., Chan, H., Zeng, J., Liu, X., Chen, H., Yu, J., Chan, F.K.L., Ng, S.C., Wong, S.H., Wang, M.H., Gin, T., Joynt, G.M., Hui, D.S.C., Zou, X., Shu, Y., Cheng, C.H.K., Fang, S., Luo, H., Lu, J., Chan, M.T.V., Zhang, L., and Wu, W.K.K. (2022). SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1. Cell Death Differ 29, 1240-1254. [IF2023=13.7]
- Chan, H., Li, Q., Wang, X., Liu, W.Y., Hu, W., Zeng, J., Xie, C., Kwong, T.N.Y., Ho, I.H.T., Liu, X., Chen, H., Yu, J., Ko, H., Chan, R.C.Y., Ip, M., Gin, T., Cheng, A.S.L., Zhang, L., Chan, M.T.V., Wong, S.H., and Wu, W.K.K. (2022). Vitamin D(3) and carbamazepine protect against Clostridioides difficile infection in mice by restoring macrophage lysosome acidification. Autophagy 18, 2050-2067. [IF2023=14.6]
- Wang, X., Chen, M., Liang, X., Bai, Y., Zeng, J., Xu, X., Li, H., Wang, J., Fan, K., and Zhao, G. (2021). RNF135 Promoter Methylation Is Associated With Immune Infiltration and Prognosis in Hepatocellular Carcinoma. Front Oncol 11, 752511. [IF2023=3.5]
- Li, Q., Hu, W., Liu, W.X., Zhao, L.Y., Huang, D., Liu, X.D., Chan, H., Zhang, Y., Zeng, J.D., Coker, O.O., Kang, W., Ng, S.S.M., Zhang, L., Wong, S.H., Gin, T., Chan, M.T.V., Wu, J.L., Yu, J., and Wu, W.K.K. (2021). Streptococcus thermophilus Inhibits Colorectal Tumorigenesis Through Secreting beta-Galactosidase. Gastroenterology 160, 1179-1193. [IF2023=25.7]
- Ho, J., Chan, H., Liang, Y., Liu, X., Zhang, L., Li, Q., Zhang, Y., Zeng, J., Ugwu, F.N., Ho, I.H.T., Hu, W., Yau, J.C.W., Wong, S.H., Wong, W.T., Ling, L., Cho, C.H., Gallo, R.L., Gin, T., Tse, G., Yu, J., Chan, M.T.V., Leung, C.C.H., and Wu, W.K.K. (2020). Cathelicidin preserves intestinal barrier function in polymicrobial sepsis. Crit Care 24, 47. [IF2023=8.8]
- Zeng, J.D., Wu, W.K.K., Wang, H.Y., and Li, X.X. (2019). Serine and one-carbon metabolism, a bridge that links mTOR signaling and DNA methylation in cancer. Pharmacol Res, 104352. [IF2023=9.1]
- Zeng, J.D., Zhang, N., Zhao, G.J., Xu, L.X., Yang, Y., Xu, X.Y., Chen, M.K., Wang, H.Y., Zheng, S.X., and Li, X.X. (2018). MT1G is Silenced by DNA Methylation and Contributes to the Pathogenesis of Hepatocellular Carcinoma. J Cancer 9, 2807-2816. [IF2023=3.3]
- Zeng, L., Liao, Q., Zou, Z., Wen, Y., Wang, J., Liu, C., He, Q., Weng, N., Zeng, J., Tang, H., Fang, R., Lei, Z., Tang, Z., Yang, X., and Cui, S. (2018). Long Non-Coding RNA XLOC_006753 Promotes the Development of Multidrug Resistance in Gastric Cancer Cells Through the PI3K/AKT/mTOR Signaling Pathway. Cell Physiol Biochem 51, 1221-1236. [IF2023=2.5]
- Jiang, C., Xu, R., Li, X.X., Wang, Y.Y., Liang, W.Q., Zeng, J.D., Zhang, S.S., Xu, X.Y., Yang, Y., Zhang, M.Y., Wang, H.Y., and Zheng, X.F.S. (2017). p53R2 overexpression in cervical cancer promotes AKT signaling and EMT, and is correlated with tumor progression, metastasis and poor prognosis. Cell cycle (Georgetown, Tex.) 16, 1673-1682. [IF2023=3.4]
Last updated on 26-05-2026

