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Warfarin

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Warfarin

Drug interactions

Potentiate effect of warfarin

- antibiotics
- cimetidine
- diazoxide
- ibuprofen
- pentoxifylline
- phenytoin

Counteract or diminish effect

- steroids
- antacids
- barbiturates
- haloperidol
- sucralfate

Conditions that prolong PT of patients on warfarin

- cancer
- collagen disease
- CCF
- diarrhoea
- fever
- hepatic disorders
- hyperthyroidism
- poor nutrition
- steatorrhoea

Conditions that decrease PT

- oedema
- hereditary warfarin resistance
- hyperlipidaemia
- hypothyroidism

Further reading

Baker RI et al. Warfarin reversal: consensus guidelines, on behalf of the Australasian Society of Thrombosis and Haemostasis. Med J Australia, 2004; 181(9):492-7

 

©Charles Gomersall, October, 2009 unless otherwise stated. The author, editor and The Chinese University of Hong Kong take no responsibility for any adverse event resulting from the use of this webpage.
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