The Dept of Anaesthesia & Intensive Care, CUHK
- 1-deamino, 8 D-arginine vasopressin.
- alters coagulation by an effect on vascular endothelium and platelets.
- larger doses sometimes required in very early phase of central DI. Possibly due to receptor blockade by biologically active precursors of ADH released by acutely damaged hypothalamic-pituitary tract.
- doubts over safety in pregnancy
Donaldson MDJ, Seaman MJ and Park GR, Massive blood transfusion. Br J Anaesth
© Charles Gomersall December 1999
April, 2014 unless
otherwise stated. The author, editor and The Chinese University of Hong Kong
take no responsibility for any adverse event resulting from the use of this